TrumpRx: Complete Guide to the New Prescription Discount Platform and Full Drug List
- Ask Medicaid Florida
- Feb 7
- 7 min read
TrumpRx is a high-profile federal initiative launched in early February 2026 by the Trump administration to make prescription medications more affordable for Americans who pay out-of-pocket — particularly uninsured patients. The platform connects users with discounted prices on select brand-name drugs through coupon codes and manufacturer direct-to-consumer pricing. Unlike insurance, TrumpRx does not sell medications directly but offers price listings and savings opportunities at pharmacies nationwide.
What Is TrumpRx and How Does It Work?
TrumpRx is a government-run drug discount website that lists prices for dozens of prescription drugs, promising Americans some of the lowest available U.S. prices by applying a “Most Favored Nation” pricing approach and direct manufacturer agreements. Users search the site, view posted prices, then print coupons or link to manufacturer programs to purchase drugs at participating pharmacies.
Key features:
Discounted out-of-pocket pricing for many high-cost drugs.
Coupon-style savings similar to other prescription discount tools.
Does not replace insurance; insurance copays and deductibles are separate.
Discounts currently apply mostly to brand-name medications.
Who Benefits Most from TrumpRx?
TrumpRx tends to benefit:
Uninsured or underinsured individuals paying cash for prescriptions.
People needing specific high-cost medications with significant list-price reductions.
Limitations include:
Not counting toward insurance deductibles or out-of-pocket maximums.
Some generic drugs may still be cheaper elsewhere with discount coupons or insurance.
Full List of Drugs on TrumpRx (43 Medications)
Below is a current list of discounted prescription medications available through TrumpRx, including drug name and typical TrumpRx price (discounted cash price).
Abrilada pen – $207.60
Airsupra – $201
Azulfidine Tabs – $99.60
Azulfidine En Tabs – $130.80
Bevespi – $51
Cetrotide – $22.50
Chantix – $106.20
Cleocin – $94.35
Colestid – $127.91
Cortef – $45
Cytomel – $6
Diflucan – $14.06
Duavee – $30.30
Estring – $249
Eucrisa – $158.48
Farxiga – $181.59
Genotropin – $89.67
Gonal F – $168
Insulin Lispro – $25
Levoxyl – $35.10
Lopid – $39.60
Medrol – $3.15
Ngenla – $2,217
Nicotrol – $271.16
Ovidrel – $84
Ozempic Pen – $199
Premarin – $99
Premarin Vaginal Cream – $236.65
Prempro – $98.84
Pristiq – $200.10
Protonix – $200.10
Tikosyn – $336
Toviaz – $43.50
Vfend – $306.98
Viracept – $607.20
Wegovy Pen – $199
Wegovy Pill – $149
Xeljanz – $1,518
Xigduo XR – $181.59
Zarontin – $71.10
Zavzpret – $594.84
Zepbound – $299
Zyvox – $122.74
Popular Medications and Discounts
Wegovy Pill & Pen: GLP-1 weight-loss/diabetes drugs with some of the deepest discounts (as much as ~89% off list price).
Ozempic: Semaglutide diabetes treatment also available at significantly lower TrumpRx prices.
Gonal F & Cetrotide: Fertility medications offered at unusually low cash prices.
Insulin Lispro: Insulin with a steep reduction compared with typical cash prices.
Tips for Using TrumpRx
Compare prices with insurance copays and other discount tools — sometimes insurance or generic coupons are cheaper.
Bring the TrumpRx coupon code to your pharmacy — not all pharmacies may participate initially.
Ask your pharmacist if alternative generics or price plans could be even less expensive.
Frequently asked questions about TrumpRx
Is TrumpRx government or private?
Trump officially unveiled TrumpRx.gov, a transformative new government platform that gives Americans direct access to dramatically lower prices on dozens of common, high-cost brand-name prescription drugs.
How much will Zepbound cost at TrumpRx?
Through the new TrumpRx platform and related deals, Zepbound (tirzepatide) for weight loss is priced around $299-$346/month, down from over $1,000/month, with further price drops expected towards $245/month as part of agreements with Eli Lilly for <<< Medicare/Medicaid>/TrumpRx> access, aiming to significantly cut costs for patients.
Key Price Points & Details
TrumpRx Launch Price: Around $299-$346 monthly for Zepbound.
Expected Medicare/Medicaid Price: Aiming for $245/month for Medicare beneficiaries and Medicaid programs.
Manufacturer Price Cuts: Eli Lilly agreed to these significant reductions in exchange for market access and tariff exemptions, lowering the cash price via their direct-to-consumer site (LillyDirect) to $299-$449/month depending on the dose.
How it Works: The TrumpRx portal directs consumers to manufacturer sites, and these deals apply to purchases through TrumpRx, Medicare, and Medicaid.
In Summary: Patients can now access Zepbound at substantially lower prices, with the $299-$346 range being the new standard through these initiatives, a major drop from its original cost.
Did Trump reduce the price of Ozempic?
Yes, the Trump administration announced significant price reductions for Ozempic (and similar GLP-1 drugs like Wegovy/Zepbound) through deals with manufacturers, lowering the cash price to around $350/month on the new TrumpRx.gov site and $245 for Medicare patients, starting in late 2025/early 2026. These cuts were negotiated via "Most Favored Nation" (MFN) agreements, aiming to make the drugs more accessible for diabetes and obesity treatment, though the rollout and specific eligibility for Medicare coverage were detailed as ongoing.
Is TrumpRx using GoodRx?
GoodRx is a core integration partner for TrumpRx, powering the pricing for leading brand medications. At launch, GoodRx is the integrated pricing source on TrumpRx for Pfizer, including over 30 of Pfizer's essential brand medications spanning women's health, arthritis, and more.
Who runs TrumpRx?
TrumpRx is a prescription drug website operated by the United States federal government.
How much is tirzepatide on Trump?
Novo Nordisk and Eli Lilly have agreed to a most-favoured nation (MFN) drug pricing deal that will make their blockbuster obesity treatments Wegovy (semaglutide) and Zepbound (tirzepatide) available on TrumpRx at $350 and $299 per month, respectively — though those prices are expected to "trend down" to $245 within two
Other important TrumpRx articles
TrumpRx promises cheap drugs for the US ― but how cheap?
The US government has launched its drug discounting program "TrumpRx" which it says will dramatically cut prescription medication prices for consumers.
It comes amid debate about cost-of-living in the US during a midterm election year. The November 2026 poll is seen as a referendum on the president's popularity, with Donald Trump's early-year approval among his lowest polling numbers ever with independent voters.
Trump has made a point of strong-arming pharmaceutical manufacturers since returning to the White House in January 2025. Read full article.
TrumpRx: See the 43 drugs available on the Trump administration's new discounted drug site
President Trump's new TrumpRx online platform is a key part of his plan to help lower drug costs for consumers, with some polls showing two-thirds of Americans report high health care costs as their chief financial concern.
Here's what to know about TrumpRx, which launched Thursday and which the White House said in a fact sheet will provide "immediate relief" to patients across the U.S. Read full article.
TrumpRx 2026: “How Americans Can Unlock Affordable Prescription Medications” Kindle Edition
A Prescription for Change — Not Just Another Healthcare Book.
Have you ever stood at a pharmacy counter, heart pounding as the total climbs higher than your rent?Do you feel powerless watching your medication costs rise while those “mystery” prices never seem to make sense?Are you tired of insurance confusion, deductibles that never seem to help, and the fear that you or someone you love might be priced out of life‑saving medicine?
If yes, then TrumpRx: How Americans Can Unlock Affordable Prescription Medications was written for you.
Important Things to Know About TrumpRx
Prices are not guaranteed long-term. TrumpRx pricing depends on voluntary manufacturer participation. Drug prices and availability can change at any time, and medications may be added or removed without notice.
Coverage is limited and selective. The platform currently includes just over 40 brand-name drugs. Thousands of commonly prescribed medications are not included, and many listed drugs already have cheaper generic alternatives elsewhere.
Pharmacy participation varies. Not all pharmacies accept TrumpRx coupons. Patients may need to call ahead or switch pharmacies to use the listed pricing.
Savings do not apply to insurance benefits. Purchases made through TrumpRx do not count toward insurance deductibles, out-of-pocket maximums, or Medicare Part D coverage thresholds.
Primarily benefits cash-pay patients. The biggest savings tend to apply to uninsured, underinsured, or high-deductible patients paying full retail prices.
Political and legal uncertainty remains. Because TrumpRx is tied to executive policy and manufacturer agreements, future administrations could modify, limit, or discontinue the program.
Price transparency, not systemic reform. Health policy analysts widely agree TrumpRx functions more like a government-backed discount directory than a structural fix to U.S. drug pricing.
TrumpRx vs GoodRx vs Insurance Comparison
Feature | TrumpRx | GoodRx | Health Insurance |
Type | Federal discount price directory | Private coupon/discount platform | Insurance benefit |
How it works | Cash-pay pricing via coupons or manufacturer links | Cash-pay coupons at participating pharmacies | Copays, coinsurance, deductibles |
Uses insurance? | No | No | Yes |
Counts toward deductible / OOP max | No | No | Yes |
Best for | Uninsured, underinsured, high-deductible patients | Cash-pay patients seeking lowest retail price | People with active coverage |
Drug selection | Limited (~40+ mostly brand-name drugs) | Very broad (brand + generic) | Very broad, plan-dependent |
Generic drugs | Limited | Strong coverage | Strong coverage |
Brand-name discounts | Select high-profile brands | Varies by pharmacy | Depends on formulary |
Pharmacy acceptance | Varies | Widely accepted | Network-based |
Price stability | Can change based on manufacturer participation | Changes frequently | More predictable |
Transparency | Posted cash prices | Estimated prices | Often opaque until checkout |
Medicare compatibility | Does not apply to Part D | Does not apply to Part D | Fully integrated |
TrumpRx makes sense for specific brand-name drugs when paying full cash.
GoodRx is usually better for generics and broader choice.
Insurance remains the best option for ongoing care and cost protection, even if sticker prices appear higher.
Who Should Use TrumpRx vs Who Shouldn’t
Should Use TrumpRx | Should Not Use TrumpRx |
Uninsured individuals paying full retail prices | People with strong employer or ACA insurance coverage |
High-deductible health plan members before meeting deductible | Patients with low fixed copays |
Patients prescribed a drug specifically listed on TrumpRx | Patients taking medications not included on the list |
Cash-pay patients needing select brand-name drugs | Patients who rely on generic medications |
People comparing prices before filling a prescription | Patients who need purchases to count toward deductibles |
Individuals without pharmacy network restrictions | Patients limited to narrow pharmacy networks |
Short-term or one-off prescriptions | People managing multiple chronic conditions |
Consumers willing to shop pharmacies | Patients wanting one predictable monthly cost |
TrumpRx can deliver meaningful savings in narrow, specific situations, primarily for cash-pay users on select brand-name medications. It is not a replacement for insurance and will often be inferior to insurance or generic discounts for routine prescriptions.
Conclusion
TrumpRx represents a high-visibility attempt to lower prescription drug costs by listing discounted prices on dozens of brand-name medications for cash-pay customers. While beneficial for certain uninsured patients and drug prices compared with list pricing, users should carefully compare savings with insurance coverage and generic discounts to ensure they are getting the best deal.
Disclaimer
This content is provided for entertainment and informational purposes only and should not be considered medical, legal, financial, or professional advice. No claims are made regarding the effectiveness, accuracy, or availability of any products, programs, or services mentioned. Always consult a qualified professional before making decisions related to health, medications, insurance, or finances. Read full disclaimer.
Ask Medicaid Florida participates in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com